AOD-9604 Specs: Sequence, MW & CAS
Part of the full AOD-9604 guide - a growth-hormone c-terminal lipolytic fragment analogue reference compound, identity-verified with a COA on every vial.
In brief
AOD-9604's molecular identifiers fix exactly what the material is and tie its structure to the lipolytic-fragment signaling it is studied for. The defining identifiers in this entry are the 16-residue sequence, the molecular weight 1815.06 g/mol, the molecular formula C78H123N23O23S2, and CAS number 221231-10-3, with the peptide classed as a growth-hormone C-terminal lipolytic fragment analogue (a synthetic 16-residue peptide).
To the molecule
Molecular specifications
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-PheThe detail
A closer look
01
Sequence and what it encodes
The sequence is Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe, sixteen residues in total. Fifteen of these correspond to the C-terminal lipolytic domain of human growth hormone (residues 176-191), and the N-terminal tyrosine (Tyr) is an added residue not part of the native fragment. Structurally, the two cysteine residues (positions 7 and 14) are the functionally critical pair: they form an intramolecular disulfide that constrains the molecule's conformation, which is the structural basis for presenting the lipolytic signaling surface in a defined shape.
02
Molecular weight and formula
The molecular formula C78H123N23O23S2 enumerates the atomic composition; the two sulfur atoms (S2) correspond to the two cysteine thiol groups that form the single intramolecular disulfide. The molecular weight of 1815.06 g/mol is consistent with a 16-residue peptide and is the value used to convert between mass and molar concentration in assay work (moles = mass / 1815.06 g/mol). These figures are the quantitative fingerprint that distinguishes AOD-9604 reference material from the intact parent hormone, which is far larger.
03
Identifier, class, and structure-function meaning
CAS number 221231-10-3 is the unique registry identifier for AOD-9604 used to confirm material identity. The peptide class - growth-hormone C-terminal lipolytic fragment analogue (synthetic 16-residue peptide) - encodes the structure-function logic directly: it is an analogue of only the C-terminal lipolytic portion of growth hormone, not the whole hormone. That is precisely why, in the models cited, it reproduces lipolytic-fragment signaling without engaging the growth-hormone receptor and without stimulating IGF-1, separating metabolic-fragment signaling from classical GH-receptor activity.
The fine print: products are sold for laboratory research use only and are not for human or animal consumption. Bodily introduction into humans or animals is strictly prohibited by law. AOD-9604 is not a drug and is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA.