AOD-9604 Half-Life & Stability
Part of the full AOD-9604 guide - a growth-hormone c-terminal lipolytic fragment analogue reference compound, identity-verified with a COA on every vial.
In brief
AOD-9604 is a small synthetic 16-residue peptide (molecular weight 1815.06 g/mol). The entry does not provide peptide-specific pharmacokinetic constants such as a measured half-life, clearance rate, or degradation kinetics, so the discussion below distinguishes what the structure supports from general small-peptide-class principles. Where a statement is a general peptide-class principle rather than an AOD-9604-specific measurement, it is labeled as such.
The detail
A closer look
01
Structural stability features supported by the data
One stability-relevant feature is documented directly: the two cysteine residues form an intramolecular disulfide that constrains the fragment's conformation. A defined disulfide-locked conformation is generally associated with a more structurally ordered peptide than an unconstrained linear chain. Beyond this conformational constraint and the molecular weight and formula (C78H123N23O23S2), the entry supplies no peptide-specific stability or degradation data, and none is invented here.
02
General small-peptide-class handling principles
As a general matter for short synthetic peptides of this size class (not an AOD-9604-specific measurement in this dataset), reconstituted aqueous peptide solutions are typically handled cold and protected from light, and freeze-thaw cycling and prolonged room-temperature exposure are generally minimized to limit aggregation and chemical degradation. Lyophilized peptide stored dry, frozen, and light-protected is generally more stable than peptide already in solution. These are class-level laboratory-handling conventions stated generally, because the entry contains no compound-specific shelf-life, half-life, or degradation-rate figures for AOD-9604.
The fine print: products are sold for laboratory research use only and are not for human or animal consumption. Bodily introduction into humans or animals is strictly prohibited by law. AOD-9604 is not a drug and is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA.