Epitalon Specs: Sequence, MW & CAS
Part of the full Epitalon guide - a synthetic linear tetrapeptide reference compound, identity-verified with a COA on every vial.
In brief
Epitalon's molecular specification is unusually clean to read because every identifier in the entry traces to the same compound record, and the structure is small enough that sequence, formula, and mass can be reconciled directly. The peptide is a synthetic linear tetrapeptide, Ala-Glu-Asp-Gly, one-letter A-E-D-G, with molecular formula C14H22N4O9, an average molecular weight of 390.35 g/mol, and CAS Registry Number 307297-39-8 (PubChem CID 219042). It is classed as a Khavinson pineal bioregulator, a short biologically active peptide modeled on the amino-acid composition of the pineal extract epithalamin and developed by the V.Kh. Khavinson group at the St. Petersburg Institute of Bioregulation and Gerontology. This spoke explains what each specification field means and how the four-residue structure connects to the molecule's reported function as a nucleic-acid-binding, gene-expression-modulating peptide rather than a receptor ligand, keeping all interpretation anchored to the provided constants.
To the molecule
Molecular specifications
Ala-Glu-Asp-Gly (AEDG)The detail
A closer look
01
Sequence and what the four residues contribute
The sequence Ala-Glu-Asp-Gly (AEDG) is a linear tetrapeptide with no cyclization or modified termini described in the entry. Reading it residue by residue: alanine provides a small hydrophobic N-terminal residue; glutamate and aspartate are the two acidic residues whose carboxylate side chains dominate the molecule's charge and water solubility; glycine, the smallest residue, terminates the chain and adds conformational flexibility. The canonical SMILES in the entry, CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N, encodes exactly this Ala-Glu-Asp-Gly backbone with free amino and carboxyl termini. The acidic glutamate-aspartate pair is structurally significant because the proposed mechanism centers on sequence-specific DNA and chromatin interaction; the side-chain chemistry of these residues is what the literature ties to nucleic-acid binding.
02
Formula, mass, and registry identifiers
The molecular formula C14H22N4O9 accounts for fourteen carbons, twenty-two hydrogens, four nitrogens, and nine oxygens, consistent with four amino acids joined by three peptide bonds and bearing two acidic side-chain carboxyls plus the free terminal groups. The average molecular weight of 390.35 g/mol follows from that formula and is the constant used for all reconstitution and concentration math. CAS Registry Number 307297-39-8 is the unique substance identifier used across ChemicalBook and BOC Sciences records, while PubChem CID 219042 is the database compound identifier linking the formula, mass, sequence, and SMILES. Together these fields let a researcher confirm they have the correct compound: the CAS number disambiguates the substance, the CID ties to the structural record, and the formula and mass cross-check the sequence.
The fine print: products are sold for laboratory research use only and are not for human or animal consumption. Bodily introduction into humans or animals is strictly prohibited by law. Epitalon is not a drug and is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA.