Ipamorelin Specs: Sequence, MW & CAS
Part of the full Ipamorelin guide - a selective growth-hormone secretagogue reference compound, identity-verified with a COA on every vial.
In brief
This spoke explains the physicochemical identifiers in the entry and what they mean structurally and functionally for ipamorelin. The data fields are: sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2; molecular weight 711.86 g/mol; molecular formula C38H49N9O5; CAS number 170851-70-4; and class designation as a selective growth-hormone secretagogue / ghrelin (GHS-R1a) receptor agonist pentapeptide. All interpretation below is grounded only in these provided identifiers.
To the molecule
Molecular specifications
Aib-His-D-2-Nal-D-Phe-Lys-NH2The detail
A closer look
01
Sequence and what each label means
The sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 defines a pentapeptide (five residues) read N-terminus to C-terminus. Aib is aminoisobutyric acid, an alpha,alpha-disubstituted non-coded residue; His is histidine; D-2-Nal is the D-configuration enantiomer of 2-naphthylalanine; D-Phe is D-phenylalanine; Lys is lysine. The terminal '-NH2' denotes a C-terminal primary amide rather than a free carboxylic acid. Two of the five residues (Aib and D-2-Nal) are the non-coded residues the entry singles out as shaping receptor interaction, and the presence of D-amino acids (D-2-Nal, D-Phe) marks this as a deliberately engineered, non-proteinogenic sequence rather than a natural peptide.
02
Molecular formula and molecular weight
The molecular formula C38H49N9O5 enumerates the atomic composition of one ipamorelin molecule: 38 carbon, 49 hydrogen, 9 nitrogen, and 5 oxygen atoms. The corresponding molecular weight is 711.86 g/mol (keyFacts sourceHint: ChemicalBook / Sigma), the mass of one mole of the compound. The relatively low nitrogen-to-carbon profile and modest molecular weight are consistent with a small synthetic pentapeptide. This molecular weight is also the conversion constant used in any mass-to-moles laboratory calculation for the compound (for example, when computing molar concentration of a prepared stock).
03
CAS number as the unique identifier
The CAS Registry Number 170851-70-4 is the unique chemical identifier assigned to ipamorelin. It serves as an unambiguous catalog and reference key that distinguishes this exact compound from structurally similar peptides and is the canonical handle for sourcing, documentation, and cross-referencing reference materials in a laboratory inventory.
04
Structure-function linkage
The structure-function story in the entry connects the sequence directly to the receptor behavior. The class designation identifies the functional role: a selective agonist at GHS-R1a (the ghrelin receptor). The selectivity that distinguishes ipamorelin from earlier secretagogues, growth-hormone release without proportional ACTH/cortisol/prolactin rise, is attributed in the data specifically to the two non-coded residues (Aib and D-2-Nal). Thus the unusual residues visible in the primary structure are the structural basis the entry assigns to the molecule's selective receptor-signaling fingerprint, tying specs to mechanism.
The fine print: products are sold for laboratory research use only and are not for human or animal consumption. Bodily introduction into humans or animals is strictly prohibited by law. Ipamorelin is not a drug and is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA.