NAD+

The longevity molecule

The coenzyme at the center of the longevity movement - for the clear focus, deep energy, and youthful vitality you feel when your cells are firing on every cylinder - third-party verified, made in the USA, lot-traceable.

$50.00· 500 mg

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Know exactly what’s in the vial.

How it works

Key electron acceptor/donor in glycolysis and the Krebs cycle, fueling ATP production.
Mandatory co-substrate for Sirtuins (SIRT1-7) regulating mitochondrial biogenesis.
Substrate for PARP enzymes involved in DNA-strand-break repair.
Precursor in CD38 / cADPR calcium-signaling pathways.

Where it shines

Mitochondrial-respiration and aging models.
DNA-integrity and genotoxic-stress studies.
Neurodegenerative-disease modeling.

The specs, on the record

Amino-acid sequenceCoenzyme (dinucleotide)

Molecular weight663.43 g/mol

Molecular formulaC21H27N7O14P2

CAS number53-84-9

Research categoryEnergy & Longevity

FormatMulti-dose vial · 500 mg

Stability & storage

Lyophilized powder - store at -20°C, protected from light.
Reconstituted - refrigerate 2-8°C; use within ~28-30 days.
Avoid repeated freeze-thaw cycles.

Backed by the science

The receipts. Peer-reviewed.

Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.

Gomes, A. P., et al. (Sinclair lab) (2013). Cell.

doi:10.1016/j.cell.2013.11.037 ↗

NAD+ intermediates: the biology and therapeutic potential of NMN and NR.

Yoshino, J., et al. (2018). Cell Metabolism.

doi:10.1016/j.cmet.2017.11.002 ↗

Every citation above is real, public, and linked. Sold for laboratory research use only; not a drug, and not intended to diagnose, treat, cure, or prevent any disease in humans.

Complete the stack

Researchers often pair NAD+ with

MOTS-c

Reciprocal headline mitochondrial-longevity pair - NAD+ substrate research co-modeled with MOTS-c signaling.

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Tesamorelin

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