MOTS-c

Cellular energy, switched on

Powered by your own mitochondria, MOTS-c is the favorite of athletes and biohackers chasing real endurance, steadier metabolism, and all-day energy - third-party verified, made in the USA, lot-traceable.

$50.00· 10 mg

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Know exactly what’s in the vial.

How it works

Triggers phosphorylation/activation of AMPK, a master energy regulator.
Promotes AICAR accumulation via folate-pathway regulation.
Promotes GLUT4 translocation linked to insulin-independent glucose uptake.
Enhances fatty-acid β-oxidation (CPT-1, acyl-CoA dehydrogenase) in models.

Where it shines

Insulin-sensitivity and metabolic-syndrome models.
Physical endurance and mitochondrial-biogenesis studies.
Cellular senescence and longevity modeling.

The specs, on the record

Amino-acid sequenceMet-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Molecular weight2174.62 g/mol

Molecular formulaC101H152N28O22S2

CAS number1627580-64-6

Research categoryEnergy & Longevity

FormatMulti-dose vial · 10 mg

Stability & storage

Lyophilized powder - store at -20°C, protected from light.
Reconstituted - refrigerate 2-8°C; use within ~28-30 days.
Avoid repeated freeze-thaw cycles.

Backed by the science

The receipts. Peer-reviewed.

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and prevents obesity and insulin resistance.

Lee, C., et al. (2015). Cell Metabolism.

doi:10.1016/j.cmet.2015.01.009 ↗

MOTS-c promotes physical performance and prevents age-associated metabolic decline.

Reynolds, J. C., et al. (2021). Nature Communications.

doi:10.1038/s41467-020-20790-0 ↗

Every citation above is real, public, and linked. Sold for laboratory research use only; not a drug, and not intended to diagnose, treat, cure, or prevent any disease in humans.

Complete the stack

Researchers often pair MOTS-c with

NAD+

The headline mitochondrial-longevity pair - MOTS-c (AMPK signaling) is explicitly co-modeled with NAD+ substrate research.

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CJC-1295 No DAC

Mitochondrial-metabolic research crossed with GH-axis research in performance literature.

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Tesamorelin

Mitochondrial-energy research documented alongside GH-axis metabolic research.

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